TRIAL OVERVIEW
TRIAL OVERVIEW
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GA-Targets trial is a randomized clinical trial investigating different targets of PEEP (Positive End Expiratory pressure), Tidal volume, FiO2 (fraction of inspired oxygen) and Blood pressure during general anesthesia.
Patients will be randomized within the domains: Blood pressure, PEEP, tidal volume, and FiO2 in a 4x3x3x2 fashion with an equal allocation ratio within each intervention domain.
This website is targeted healthcare professionals involved in GA-Targets Trial.
If you are a patient or a relative seeking information go to:
The flow chart below provides an overview of inclusion- and exclusion criteria, interventions and primary and secondary outcomes.
a: Planned endothracheal intubation with positive pressure ventilation
b: Abdominal, urogenital, gynecological surgeries: Laporascopic or open abdominal surgery. Orthepedic and neurological surgery: Spine, pelvis or collum/corpus femoris. Vascular surgery: Open surgery in the abdomen, pelvis or leg.
c: Clinical judgement by the anesthesiologist
The figure below provides information on duration of interventions, time of blood samples and follow-up.
*Blood analyses include: CRP, leucocytes, troponin I (TnI), aminotransferase levels (ALT), creatinine and albumin.
Abbreviations: TV: Tidal volume, BP: Blood pressure,PACU: Post-anesthesia care unit. ICU: Intensive care unit.
UPDATES
UPDATES
April 12, 2024. Trial start in Aalborg N
January 08, 2024. 51 patients included in GA-Targets Trial.
December 21, 2023. 44 patients included in GA-Targets Trial.
December 15, 2023. Trial start Aarhus
December 14, 2023. 37 patients included in GA-Targets Trial.
December 04, 2023. 31 patients included in GA-Targets Trial.
November 20, 2023. Trial start in Viborg
November 15, 2023. 21 patients included in GA-Targets Trial.
October 31, 2023. Trial start in Horsens.
October 9, 2023. Trial start in Randers. 1. patient included.
June 28, 2023. Approvel from Regional Ethics Commitee
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