BLINDING

The trial is single-blind. The patient is anesthetized and therefore not aware of the allocation. The treating anesthesia and postoperative teams will not be blinded to the intervention. The surgical team will not be directly informed about the interventions unless clinical indicated. Assessors of postoperative complications obtained from the electronical medical journal will not be directly informed of the intervention, however, information regarding the interventions could be described in the electronical medical record. The outcomes are generally objective and not subject to a large degree of individual interpretation; therefore, we do not consider this a problem for the validity of reported outcomes. The personnel who will perform follow-up at day 30 and day 90 will be blinded to the intervention.